Cargando…

β Integrins Mediate FAK Y397 Autophosphorylation of Resistance Arteries during Eutrophic Inward Remodeling in Hypertension

Human essential hypertension is characterized by eutrophic inward remodeling of the resistance arteries with little evidence of hypertrophy. Upregulation of αVβ3 integrin is crucial during this process. In order to investigate the role of focal adhesion kinase (FAK) activation in this process, the l...

Descripción completa

Detalles Bibliográficos
Autores principales: Heerkens, Egidius H.J, Quinn, Lisa, Withers, Sarah B, Heagerty, Anthony M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224252/
https://www.ncbi.nlm.nih.gov/pubmed/25300309
http://dx.doi.org/10.1159/000365479