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β Integrins Mediate FAK Y397 Autophosphorylation of Resistance Arteries during Eutrophic Inward Remodeling in Hypertension
Human essential hypertension is characterized by eutrophic inward remodeling of the resistance arteries with little evidence of hypertrophy. Upregulation of αVβ3 integrin is crucial during this process. In order to investigate the role of focal adhesion kinase (FAK) activation in this process, the l...
Autores principales: | Heerkens, Egidius H.J, Quinn, Lisa, Withers, Sarah B, Heagerty, Anthony M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224252/ https://www.ncbi.nlm.nih.gov/pubmed/25300309 http://dx.doi.org/10.1159/000365479 |
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