Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype

Adipose tissue plays an essential role in metabolic homeostasis and holds promise as an alternative depot organ in gene therapy. However, efficient methods of gene transfer into adipose tissue in vivo have yet to be established. Here, we assessed the transduction efficiency to fat depots by a family...

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Detalles Bibliográficos
Autores principales: Liu, Xianglan, Magee, Daniel, Wang, Chuansong, McMurphy, Travis, Slater, Andrew, During, Matthew, Cao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224270/
https://www.ncbi.nlm.nih.gov/pubmed/25383359
http://dx.doi.org/10.1038/mtm.2013.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224270/
https://www.ncbi.nlm.nih.gov/pubmed/25383359
http://dx.doi.org/10.1038/mtm.2013.8

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