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Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype
Adipose tissue plays an essential role in metabolic homeostasis and holds promise as an alternative depot organ in gene therapy. However, efficient methods of gene transfer into adipose tissue in vivo have yet to be established. Here, we assessed the transduction efficiency to fat depots by a family...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224270/ https://www.ncbi.nlm.nih.gov/pubmed/25383359 http://dx.doi.org/10.1038/mtm.2013.8 |