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Elucidating the Genotype–Phenotype Relationships and Network Perturbations of Human Shared and Specific Disease Genes from an Evolutionary Perspective

To date, numerous studies have been attempted to determine the extent of variation in evolutionary rates between human disease and nondisease (ND) genes. In our present study, we have considered human autosomal monogenic (Mendelian) disease genes, which were classified into two groups according to t...

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Detalles Bibliográficos
Autores principales: Begum, Tina, Ghosh, Tapash Chandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224346/
https://www.ncbi.nlm.nih.gov/pubmed/25287147
http://dx.doi.org/10.1093/gbe/evu220