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The Influence of Selection for Protein Stability on dN/dS Estimations

Understanding the relative contributions of various evolutionary processes—purifying selection, neutral drift, and adaptation—is fundamental to evolutionary biology. A common metric to distinguish these processes is the ratio of nonsynonymous to synonymous substitutions (i.e., dN/dS) interpreted fro...

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Detalles Bibliográficos
Autores principales: Dasmeh, Pouria, Serohijos, Adrian W.R., Kepp, Kasper P., Shakhnovich, Eugene I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224349/
https://www.ncbi.nlm.nih.gov/pubmed/25355808
http://dx.doi.org/10.1093/gbe/evu223