3D Cultures of Prostate Cancer Cells Cultured in a Novel High-Throughput Culture Platform Are More Resistant to Chemotherapeutics Compared to Cells Cultured in Monolayer

Despite monolayer cultures being widely used for cancer drug development and testing, 2D cultures tend to be hypersensitive to chemotherapy and are relatively poor predictors of whether a drug will provide clinical benefit. Whilst generally more complicated, three dimensional (3D) culture systems of...

Descripción completa

Detalles Bibliográficos
Autores principales: Chambers, Karen F., Mosaad, Eman M. O., Russell, Pamela J., Clements, Judith A., Doran, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224379/
https://www.ncbi.nlm.nih.gov/pubmed/25380249
http://dx.doi.org/10.1371/journal.pone.0111029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224379/
https://www.ncbi.nlm.nih.gov/pubmed/25380249
http://dx.doi.org/10.1371/journal.pone.0111029

Ejemplares similares