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Development of a Mimotope Vaccine Targeting the Staphylococcus aureus Quorum Sensing Pathway

A major hurdle in vaccine development is the difficulty in identifying relevant target epitopes and then presenting them to the immune system in a context that mimics their native conformation. We have engineered novel virus-like-particle (VLP) technology that is able to display complex libraries of...

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Detalles Bibliográficos
Autores principales: O’Rourke, John P., Daly, Seth M., Triplett, Kathleen D., Peabody, David, Chackerian, Bryce, Hall, Pamela R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224382/
https://www.ncbi.nlm.nih.gov/pubmed/25379726
http://dx.doi.org/10.1371/journal.pone.0111198