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Development of a Mimotope Vaccine Targeting the Staphylococcus aureus Quorum Sensing Pathway
A major hurdle in vaccine development is the difficulty in identifying relevant target epitopes and then presenting them to the immune system in a context that mimics their native conformation. We have engineered novel virus-like-particle (VLP) technology that is able to display complex libraries of...
Autores principales: | O’Rourke, John P., Daly, Seth M., Triplett, Kathleen D., Peabody, David, Chackerian, Bryce, Hall, Pamela R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224382/ https://www.ncbi.nlm.nih.gov/pubmed/25379726 http://dx.doi.org/10.1371/journal.pone.0111198 |
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