Cargando…
Novel Roles for P53 in the Genesis and Targeting of Tetraploid Cancer Cells
Tetraploid (4N) cells are considered important in cancer because they can display increased tumorigenicity, resistance to conventional therapies, and are believed to be precursors to whole chromosome aneuploidy. It is therefore important to determine how tetraploid cancer cells arise, and how to tar...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224386/ https://www.ncbi.nlm.nih.gov/pubmed/25380055 http://dx.doi.org/10.1371/journal.pone.0110844 |