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Potential Compensation among Group I PAK Members in Hindlimb Ischemia and Wound Healing

PAKs are serine/threonine kinases that regulate cytoskeletal dynamics and cell migration. PAK1 is activated by binding to the small EF hand protein, CIB1, or to the Rho GTPases Rac1 or Cdc42. The role of PAK1 in angiogenesis was established based only on in vitro studies and its role in angiogenesis...

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Detalles Bibliográficos
Autores principales: Elsherif, Laila, Ozler, Mehmet, Zayed, Mohamed A., Shen, Jessica H., Chernoff, Jonathan, Faber, James E., Parise, Leslie V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224450/
https://www.ncbi.nlm.nih.gov/pubmed/25379771
http://dx.doi.org/10.1371/journal.pone.0112239