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The Drosophila Midkine/Pleiotrophin Homologues Miple1 and Miple2 Affect Adult Lifespan but Are Dispensable for Alk Signaling during Embryonic Gut Formation

Midkine (MDK) and Pleiotrophin (PTN) are small heparin-binding cytokines with closely related structures. The Drosophila genome harbours two genes encoding members of the MDK/PTN family of proteins, known as miple1 and miple2. We have investigated the role of Miple proteins in vivo, in particular wi...

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Detalles Bibliográficos
Autores principales: Hugosson, Fredrik, Sjögren, Camilla, Birve, Anna, Hedlund, Ludmilla, Eriksson, Therese, Palmer, Ruth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224452/
https://www.ncbi.nlm.nih.gov/pubmed/25380037
http://dx.doi.org/10.1371/journal.pone.0112250