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The Drosophila Midkine/Pleiotrophin Homologues Miple1 and Miple2 Affect Adult Lifespan but Are Dispensable for Alk Signaling during Embryonic Gut Formation
Midkine (MDK) and Pleiotrophin (PTN) are small heparin-binding cytokines with closely related structures. The Drosophila genome harbours two genes encoding members of the MDK/PTN family of proteins, known as miple1 and miple2. We have investigated the role of Miple proteins in vivo, in particular wi...
Autores principales: | Hugosson, Fredrik, Sjögren, Camilla, Birve, Anna, Hedlund, Ludmilla, Eriksson, Therese, Palmer, Ruth H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224452/ https://www.ncbi.nlm.nih.gov/pubmed/25380037 http://dx.doi.org/10.1371/journal.pone.0112250 |
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