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miR-18a Inhibits CDC42 and Plays a Tumour Suppressor Role in Colorectal Cancer Cells

The miR-17-92 cluster of microRNAs is elevated in colorectal cancer, and has a causative role in cancer development. Of the six miR-17-92 cluster members, miR-19a and b in particular are key promoters of cancer development and cell proliferation, while preliminary evidence suggests that miR-18a may...

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Detalles Bibliográficos
Autores principales: Humphreys, Karen J., McKinnon, Ross A., Michael, Michael Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224453/
https://www.ncbi.nlm.nih.gov/pubmed/25379703
http://dx.doi.org/10.1371/journal.pone.0112288