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Reconciling the regulatory role of Munc18 proteins in SNARE-complex assembly

Membrane fusion is essential for human health, playing a vital role in processes as diverse as neurotransmission and blood glucose control. Two protein families are key: (1) the Sec1p/Munc18 (SM) and (2) the soluble N-ethylmaleimide-sensitive attachment protein receptor (SNARE) proteins. Whilst the...

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Detalles Bibliográficos
Autores principales: Rehman, Asma, Archbold, Julia K., Hu, Shu-Hong, Norwood, Suzanne J., Collins, Brett M., Martin, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224468/
https://www.ncbi.nlm.nih.gov/pubmed/25485130
http://dx.doi.org/10.1107/S2052252514020727