Reduction of T Cell Receptor Diversity in NOD Mice Prevents Development of Type 1 Diabetes but Not Sjögren’s Syndrome

Non-obese diabetic (NOD) mice are well-established models of independently developing spontaneous autoimmune diseases, Sjögren’s syndrome (SS) and type 1 diabetes (T1D). The key determining factor for T1D is the strong association with particular MHCII molecule and recognition by diabetogenic T cell...

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Detalles Bibliográficos
Autores principales: Kern, Joanna, Drutel, Robert, Leanhart, Silvia, Bogacz, Marek, Pacholczyk, Rafal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224485/
https://www.ncbi.nlm.nih.gov/pubmed/25379761
http://dx.doi.org/10.1371/journal.pone.0112467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224485/
https://www.ncbi.nlm.nih.gov/pubmed/25379761
http://dx.doi.org/10.1371/journal.pone.0112467

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