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Anti-Angiogenic Effects of a Mutant Endostatin: A New Prospect for Treating Retinal and Choroidal Neovascularization

PURPOSE: Pathological fundus angiogenesis is a major cause of vision loss in retina diseases. Endostatin, a C-terminal fragment of collagen XVIII, is an endogenous anti-angiogenic protein. The present study aimed to investigate the in vitro and in vivo anti-angiogenic properties of two proteins: an...

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Detalles Bibliográficos
Autores principales: Bai, Yujing, Zhao, Min, Zhang, Chunfang, Li, Shanshan, Qi, Yun, Wang, Bin, Huang, Lvzhen, Li, Xiaoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224489/
https://www.ncbi.nlm.nih.gov/pubmed/25380141
http://dx.doi.org/10.1371/journal.pone.0112448