Elongation factor-2 kinase regulates TG2/β1 integrin/Src/uPAR pathway and epithelial–mesenchymal transition mediating pancreatic cancer cells invasion

Pancreatic ductal adenocarcinoma is one of the lethal cancers with extensive local tumour invasion, metastasis, early systemic dissemination and poorest prognosis. Thus, understanding the mechanisms regulating invasion/metastasis and epithelial–mesenchymal transition (EMT), is the key for developing...

Descripción completa

Detalles Bibliográficos
Autores principales: Ashour, Ahmed A, Gurbuz, Nilgun, Alpay, Sultan Neslihan, Abdel-Aziz, Abdel-Aziz H, Mansour, Ahmed M, Huo, Longfei, Ozpolat, Bulent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224557/
https://www.ncbi.nlm.nih.gov/pubmed/25215932
http://dx.doi.org/10.1111/jcmm.12361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224557/
https://www.ncbi.nlm.nih.gov/pubmed/25215932
http://dx.doi.org/10.1111/jcmm.12361

Ejemplares similares