PET Imaging of Fatty Acid Amide Hydrolase with [(18)F]DOPP in Nonhuman Primates

[Image: see text] Fatty acid amide hydrolase (FAAH) regulates endocannabinoid signaling. [(11)C]CURB, an irreversibly binding FAAH inhibitor, has been developed for clinical research imaging with PET. However, no fluorine-18 labeled radiotracer for FAAH has yet advanced to human studies. [(18)F]DOPP...

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Detalles Bibliográficos
Autores principales: Rotstein, Benjamin H., Wey, Hsiao-Ying, Shoup, Timothy M., Wilson, Alan A., Liang, Steven H., Hooker, Jacob M., Vasdev, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224570/
https://www.ncbi.nlm.nih.gov/pubmed/25004399
http://dx.doi.org/10.1021/mp500316h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224570/
https://www.ncbi.nlm.nih.gov/pubmed/25004399
http://dx.doi.org/10.1021/mp500316h

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