Cargando…

Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells

Post-transcriptional modification of RNA nucleosides occurs in all living organisms. Pseudouridine, the most abundant modified nucleoside in non-coding RNAs(1), enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure(2–8). mRNAs were not known to contain pseudouridine, b...

Descripción completa

Detalles Bibliográficos
Autores principales: Carlile, Thomas M., Rojas-Duran, Maria F., Zinshteyn, Boris, Shin, Hakyung, Bartoli, Kristen M., Gilbert, Wendy V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224642/
https://www.ncbi.nlm.nih.gov/pubmed/25192136
http://dx.doi.org/10.1038/nature13802