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Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells
Post-transcriptional modification of RNA nucleosides occurs in all living organisms. Pseudouridine, the most abundant modified nucleoside in non-coding RNAs(1), enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure(2–8). mRNAs were not known to contain pseudouridine, b...
Autores principales: | Carlile, Thomas M., Rojas-Duran, Maria F., Zinshteyn, Boris, Shin, Hakyung, Bartoli, Kristen M., Gilbert, Wendy V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224642/ https://www.ncbi.nlm.nih.gov/pubmed/25192136 http://dx.doi.org/10.1038/nature13802 |
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