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Effects of Treatment with Platinum Azidothymidine and Azidothymidine on Telomerase Activity and Bcl-2 Concentration in Hepatocellular Carcinoma- Induced Rats

BACKGROUND: Telomerase activity increases in cancer cells. Bcl-2 is an antiapoptotic factor that its concentration grows in many cancer cells including hepato-cellular carcinoma cells. In this study, an attempt was made to investigate the effects of a new synthetic compound, platinum azidothymidine...

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Detalles Bibliográficos
Autores principales: Sabokrouh, Abdolreza, Goodarzi, Mohammad Taghi, Vaisi-Raygani, Asad, Khatami, Shohreh, Taghizadeh-Jahed, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Avicenna Research Institute 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224659/
https://www.ncbi.nlm.nih.gov/pubmed/25414782