Novel self assembling nanoparticles for the oral administration of fondaparinux: Synthesis, characterization and in vivo evaluation

Fondaparinux (Fpx) is the anticoagulant of choice in the treatment of short- and medium-term thromboembolic disease. To overcome the low oral bioavailability of Fpx, a new nanoparticulate carrier has been developed. The nanoparticles (NPs) contain squalenyl derivatives, known for their excellent ora...

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Detalles Bibliográficos
Autores principales: Ralay-Ranaivo, Bettina, Desmaële, Didier, Bianchini, Elsa P., Lepeltier, Elise, Bourgaux, Claudie, Borgel, Delphine, Pouget, Thierry, Tranchant, Jean François, Couvreur, Patrick, Gref, Ruxandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Publishers 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224687/
https://www.ncbi.nlm.nih.gov/pubmed/25127657
http://dx.doi.org/10.1016/j.jconrel.2014.07.060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224687/
https://www.ncbi.nlm.nih.gov/pubmed/25127657
http://dx.doi.org/10.1016/j.jconrel.2014.07.060

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