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OncoCis: annotation of cis-regulatory mutations in cancer

Whole genome sequencing has enabled the identification of thousands of somatic mutations within non-coding genomic regions of individual cancer samples. However, identification of mutations that potentially alter gene regulation remains a major challenge. Here we present OncoCis, a new method that e...

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Detalles Bibliográficos
Autores principales: Perera, Dilmi, Chacon, Diego, Thoms, Julie AI, Poulos, Rebecca C, Shlien, Adam, Beck, Dominik, Campbell, Peter J, Pimanda, John E, Wong, Jason WH
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224696/
https://www.ncbi.nlm.nih.gov/pubmed/25298093
http://dx.doi.org/10.1186/s13059-014-0485-0