Clinical Impact of Checkpoint Inhibitors as Novel Cancer Therapies

Immune responses are tightly regulated via signaling through numerous co-stimulatory and co-inhibitory molecules. Exploitation of these immune checkpoint pathways is one of the mechanisms by which tumors evade and/or escape the immune system. A growing understanding of the biology of immune checkpoi...

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Detalles Bibliográficos
Autores principales: Shih, Kent, Arkenau, Hendrik-Tobias, Infante, Jeffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Leading Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224737/
https://www.ncbi.nlm.nih.gov/pubmed/25344022
http://dx.doi.org/10.1007/s40265-014-0305-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224737/
https://www.ncbi.nlm.nih.gov/pubmed/25344022
http://dx.doi.org/10.1007/s40265-014-0305-6

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