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Clinical Impact of Checkpoint Inhibitors as Novel Cancer Therapies
Immune responses are tightly regulated via signaling through numerous co-stimulatory and co-inhibitory molecules. Exploitation of these immune checkpoint pathways is one of the mechanisms by which tumors evade and/or escape the immune system. A growing understanding of the biology of immune checkpoi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224737/ https://www.ncbi.nlm.nih.gov/pubmed/25344022 http://dx.doi.org/10.1007/s40265-014-0305-6 |