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Stimulation-induced ectopicity and propagation windows in model damaged axons

Neural tissue injuries render voltage-gated Na(+) channels (Nav) leaky, thereby altering excitability, disrupting propagation and causing neuropathic pain related ectopic activity. In both recombinant systems and native excitable membranes, membrane damage causes the kinetically-coupled activation a...

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Detalles Bibliográficos
Autores principales: Lachance, Mathieu, Longtin, André, Morris, Catherine E., Yu, Na, Joós, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224747/
https://www.ncbi.nlm.nih.gov/pubmed/25110188
http://dx.doi.org/10.1007/s10827-014-0521-9