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Stimulation-induced ectopicity and propagation windows in model damaged axons
Neural tissue injuries render voltage-gated Na(+) channels (Nav) leaky, thereby altering excitability, disrupting propagation and causing neuropathic pain related ectopic activity. In both recombinant systems and native excitable membranes, membrane damage causes the kinetically-coupled activation a...
Autores principales: | Lachance, Mathieu, Longtin, André, Morris, Catherine E., Yu, Na, Joós, Béla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224747/ https://www.ncbi.nlm.nih.gov/pubmed/25110188 http://dx.doi.org/10.1007/s10827-014-0521-9 |
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