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First prospective comparison of genotypic vs phenotypic tropism assays in predicting virologic responses to Maraviroc (MVC) in a phase 3 study: MODERN

INTRODUCTION: MODERN (A4001095) was the first prospective phase 3 study comparing genotype vs phenotype (Trofile™) tropism assessments. MATERIALS AND METHODS: Treatment-naïve adults with HIV-1 RNA >1000 copies/mL were randomized 1:1 at screening to either genotype or Trofile for tropism assessmen...

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Detalles Bibliográficos
Autores principales: Heera, Jayvant, Valluri, Srinivas, Craig, Charles, Fang, Annie, Thomas, Neal, Meyer, Ralph Dan, Demarest, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224775/
https://www.ncbi.nlm.nih.gov/pubmed/25394028
http://dx.doi.org/10.7448/IAS.17.4.19519