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Clinical significance of the UGT1A1*28 allele detection in HIV-infected patients

INTRODUCTION: The UGT1A1*28 (rs8175347) polymorphism is associated with hyperbilirubinemia. The presence of 6 TA-repeats in the UGT1A1 gene promoter region corresponds to normal UGT1TA1 activity. A detection of 7 TA-repeats in hetero- or homozygous individuals [(TA)6/(TA)7 and (TA)7/(TA)7] is associ...

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Detalles Bibliográficos
Autores principales: Kanestri, Veronika, Mironov, Konstantin, Kravchenko, Alexey, Pokrovskaya, Anastasiya, Dribnohodova, Olga, Dunayeva, Elena, Tsiganova, Galina, Harbutly, Marina, Goliusova, Marina, Konnov, Vladislav, Kozirina, Nadezhda, Shahgildyan, Vasiliy, Kuimova, Ulyana, Popova, Anna, Efremova, Oksana, Konnov, Danila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224789/
https://www.ncbi.nlm.nih.gov/pubmed/25394086
http://dx.doi.org/10.7448/IAS.17.4.19579