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Efavirenz- but not nevirapine-based antiretroviral therapy decreases exposure to the levonorgestrel released from a sub-dermal contraceptive implant

INTRODUCTION: Sub-dermal hormone implants, such as levonorgestrel (LNG), are a safe and desirable form of long-acting contraception, but their use among HIV-positive women on antiretroviral therapy (ART) may be compromised given the potential for a cytochrome P450 3A-mediated drug–drug interaction....

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Detalles Bibliográficos
Autores principales: Scarsi, Kimberly, Lamorde, Mohammed, Darin, Kristin, Dilly Penchala, Sujan, Else, Laura, Nakalema, Shadia, Byakika-Kibwika, Pauline, Khoo, Saye, Cohn, Susan, Merry, Concepta, Back, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224805/
https://www.ncbi.nlm.nih.gov/pubmed/25393993
http://dx.doi.org/10.7448/IAS.17.4.19484