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Efavirenz- but not nevirapine-based antiretroviral therapy decreases exposure to the levonorgestrel released from a sub-dermal contraceptive implant
INTRODUCTION: Sub-dermal hormone implants, such as levonorgestrel (LNG), are a safe and desirable form of long-acting contraception, but their use among HIV-positive women on antiretroviral therapy (ART) may be compromised given the potential for a cytochrome P450 3A-mediated drug–drug interaction....
Autores principales: | Scarsi, Kimberly, Lamorde, Mohammed, Darin, Kristin, Dilly Penchala, Sujan, Else, Laura, Nakalema, Shadia, Byakika-Kibwika, Pauline, Khoo, Saye, Cohn, Susan, Merry, Concepta, Back, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International AIDS Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224805/ https://www.ncbi.nlm.nih.gov/pubmed/25393993 http://dx.doi.org/10.7448/IAS.17.4.19484 |
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