Simulation of the impact of rifampicin on darunavir/ritonavir PK and dose adjustment strategies in HIV-infected patients: a population PK approach

INTRODUCTION: Treatment of HIV/TB co-infection is challenging due to high drug–drug interaction potential between antiretrovirals and rifamycins, such as rifampicin (RIF). The PK interaction between darunavir/ritonavir (DRV/RTV) and RIF has not been studied. Utilizing other protease inhibitor data,...

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Detalles Bibliográficos
Autores principales: Dickinson, Laura, Winston, Alan, Boffito, Marta, Khoo, Saye, Back, David, Siccardi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Poster Sessions – Abstract P054
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224831/
https://www.ncbi.nlm.nih.gov/pubmed/25394092
http://dx.doi.org/10.7448/IAS.17.4.19586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224831/
https://www.ncbi.nlm.nih.gov/pubmed/25394092
http://dx.doi.org/10.7448/IAS.17.4.19586

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