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Evaluation of drug-drug interaction between daclatasvir and methadone or buprenorphine/naloxone

INTRODUCTION: Daclatasvir (DCV) is a potent hepatitis C virus (HCV) NS5A replication complex inhibitor with pangenotypic (1–6) activity in vitro. Methadone (MET) and buprenorphine (BUP) are opioid medications used to treat opioid addiction; patients on HCV therapy may require MET or BUP treatment. T...

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Detalles Bibliográficos
Autores principales: Garimella, Tushar, Wang, Reena, Luo, Wen-Lin, Wastall, Philip, Kandoussi, Hamza, Demicco, Michael, Bruce, Douglas, Hwang, Carey, Bertz, Richard, Bifano, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224839/
https://www.ncbi.nlm.nih.gov/pubmed/25394132
http://dx.doi.org/10.7448/IAS.17.4.19628