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Evaluation of drug-drug interaction between daclatasvir and methadone or buprenorphine/naloxone
INTRODUCTION: Daclatasvir (DCV) is a potent hepatitis C virus (HCV) NS5A replication complex inhibitor with pangenotypic (1–6) activity in vitro. Methadone (MET) and buprenorphine (BUP) are opioid medications used to treat opioid addiction; patients on HCV therapy may require MET or BUP treatment. T...
Autores principales: | Garimella, Tushar, Wang, Reena, Luo, Wen-Lin, Wastall, Philip, Kandoussi, Hamza, Demicco, Michael, Bruce, Douglas, Hwang, Carey, Bertz, Richard, Bifano, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International AIDS Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224839/ https://www.ncbi.nlm.nih.gov/pubmed/25394132 http://dx.doi.org/10.7448/IAS.17.4.19628 |
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