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Darunavir pharmacokinetics throughout pregnancy and postpartum

INTRODUCTION: Antiretroviral therapy is recommended during pregnancy for prevention of mother-to-child transmission (MTCT) of HIV. Physiological changes during pregnancy are known to affect the pharmacokinetics (PK) of protease inhibitors (PIs), leading to lower exposures in pregnant women. Here we...

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Detalles Bibliográficos
Autores principales: Lambert, John, Jackson, Valerie, Else, Laura, Lawless, Mairead, McDonald, Grainne, Le Blanc, Dave, Patel, Anjali, Stephens, Kelly, Khoo, Saye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224853/
https://www.ncbi.nlm.nih.gov/pubmed/25393994
http://dx.doi.org/10.7448/IAS.17.4.19485