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CSF LPV concentrations and viral load in viral suppressed patients on LPV/r monotherapy given once daily
INTRODUCTION: Plasma trough concentrations of lopinavir (LPV) given as LPV/r 800/200 mg once daily (OD) are reduced in comparison with 400/100 mg twice daily (BID). While OD dosage of LPV/r is sufficient to achieve viral suppression in plasma, data about drug penetration and viral suppression in cen...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International AIDS Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224921/ https://www.ncbi.nlm.nih.gov/pubmed/25394093 http://dx.doi.org/10.7448/IAS.17.4.19587 |