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Candesartan Attenuates Ischemic Brain Edema and Protects the Blood–Brain Barrier Integrity from Ischemia/Reperfusion Injury in Rats

Background: Angiotensin II (Ang II) has an important role on cerebral microcirculation; however, its direct roles in terms of ischemic brain edema need to be clarified. This study evaluated the role of central Ang II by using candesartan, as an AT1 receptor blocker, in the brain edema formation and...

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Detalles Bibliográficos
Autores principales: Panahpour, Hamdollah, Nekooeian, Ali Akbar, Dehghani, Gholam Abbas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225063/
https://www.ncbi.nlm.nih.gov/pubmed/25326022
http://dx.doi.org/10.6091/ibj.13672.2014