A 40-bp Insertion/Deletion Polymorphism of Murine Double Minute2 (MDM2) Increased the Risk of Breast Cancer in Zahedan, Southeast Iran

Background: MDM2 (Murine Double Minute2) is an oncoprotein that inhibits the P53 activity. Overexpression of MDM2 gene has been reported in several human tumors. In the present study, we aimed to evaluate the impact of 40-bp insertion/deletion (ins/del) polymorphism on the promoter of MDM2 and susce...

Descripción completa

Detalles Bibliográficos
Autores principales: Hashemi, Mohammad, Omrani, Mohsen, Eskandari-Nasab, Ebrahim, Hasani, Seyed-Shahaboddin, Mashhadi, Mohammad Ali, Taheri, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225065/
https://www.ncbi.nlm.nih.gov/pubmed/25326024
http://dx.doi.org/10.6091/ibj.13332.2014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225065/
https://www.ncbi.nlm.nih.gov/pubmed/25326024
http://dx.doi.org/10.6091/ibj.13332.2014

Ejemplares similares