Exendin-4 protects retinal cells from early diabetes in Goto-Kakizaki rats by increasing the Bcl-2/Bax and Bcl-xL/Bax ratios and reducing reactive gliosis

PURPOSE: Exendin-4 (E4), a long-acting agonist of the hormone glucagon-like peptide 1 receptor (GLP-1R), is administered to treat type II diabetes in the clinical setting and also shows a neuroprotective effect. Our previous studies demonstrated its protective effect in early experimental diabetic r...

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Detalles Bibliográficos
Autores principales: Fan, Yichao, Liu, Kun, Wang, Qingping, Ruan, Yuanyuan, Zhang, Yu, Ye, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225140/
https://www.ncbi.nlm.nih.gov/pubmed/25489228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225140/
https://www.ncbi.nlm.nih.gov/pubmed/25489228

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