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Lack of dystrophin protein Dp71 results in progressive cataract formation due to loss of fiber cell organization

PURPOSE: Dp71 is the main product of the Duchenne muscular dystrophy (DMD) gene in the central nervous system. While studying the impact of its absence on retinal functions, we discovered that mice lacking Dp71 also developed a progressive opacification of the crystalline lens. The purpose of this s...

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Detalles Bibliográficos
Autores principales: Fort, Patrice E., Darche, Marie, Sahel, José-Alain, Rendon, Alvaro, Tadayoni, Ramin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225142/
https://www.ncbi.nlm.nih.gov/pubmed/25489223