Different effects of valproic acid on photoreceptor loss in Rd1 and Rd10 retinal degeneration mice

PURPOSE: The histone-deacetylase inhibitor activity of valproic acid (VPA) was discovered after VPA’s adoption as an anticonvulsant. This generated speculation for VPA’s potential to increase the expression of neuroprotective genes. Clinical trials for retinitis pigmentosa (RP) are currently active,...

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Detalles Bibliográficos
Autores principales: Mitton, Kenneth P., Guzman, Alvaro E., Deshpande, Mrinalini, Byrd, David, DeLooff, Camryn, Mkoyan, Kristina, Zlojutro, Paul, Wallace, Adrianne, Metcalf, Brandon, Laux, Kirsten, Sotzen, Jason, Tran, Trung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225157/
https://www.ncbi.nlm.nih.gov/pubmed/25489226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225157/
https://www.ncbi.nlm.nih.gov/pubmed/25489226

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