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Early clinical response and presence of viral resistant minority variants: a proof of concept study

INTRODUCTION: Traditional genotyping assays detect viral variants present in at least 15–25% of the entire virus population. We tested the Next generation GS Junior System (NGS) setted with a detection limit of 0.05% and evaluated the clinical relevance of low prevalent mutations. METHODS: NGS was p...

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Detalles Bibliográficos
Autores principales: Callegaro, Annapaola, Di Filippo, Elisa, Astuti, Noemi, Andrea Serna Ortega, Paula, Rizzi, Marco, Farina, Claudio, Valenti, Daniela, Maggiolo, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225251/
https://www.ncbi.nlm.nih.gov/pubmed/25397504
http://dx.doi.org/10.7448/IAS.17.4.19759