Cargando…

HIV-1 tat and rev upregulates osteoclast bone resorption

INTRODUCTION: Disruption in bone homeostasis with increased osteoclastic resorption may lead to osteoporosis. HIV tat has been found to increase differentiation of precursor cells into osteoclast (OC) [1]. Presence of soluble HIV proteins in virally suppressed HIV patients on ART may drive a bone re...

Descripción completa

Detalles Bibliográficos
Autores principales: Chew, Nicholas, Tan, Eemin, Li, Lei, Lim, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225338/
https://www.ncbi.nlm.nih.gov/pubmed/25397470
http://dx.doi.org/10.7448/IAS.17.4.19724