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HIV-1 tat and rev upregulates osteoclast bone resorption
INTRODUCTION: Disruption in bone homeostasis with increased osteoclastic resorption may lead to osteoporosis. HIV tat has been found to increase differentiation of precursor cells into osteoclast (OC) [1]. Presence of soluble HIV proteins in virally suppressed HIV patients on ART may drive a bone re...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International AIDS Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225338/ https://www.ncbi.nlm.nih.gov/pubmed/25397470 http://dx.doi.org/10.7448/IAS.17.4.19724 |