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Central nervous system penetration-effectiveness rank does not reliably predict neurocognitive impairment in HIV-infected individuals
INTRODUCTION: Central nervous system (CNS) penetration-effectiveness (CPE) rank was proposed in 2008 as an estimate of penetration of ARV regimen into the CNS, and validated as predictor of CSF HIV-1 replication. Results on predictive role of CPE on neurocognitive and clinical outcome were conflicti...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International AIDS Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225401/ https://www.ncbi.nlm.nih.gov/pubmed/25394159 http://dx.doi.org/10.7448/IAS.17.4.19655 |