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Central nervous system penetration-effectiveness rank does not reliably predict neurocognitive impairment in HIV-infected individuals

INTRODUCTION: Central nervous system (CNS) penetration-effectiveness (CPE) rank was proposed in 2008 as an estimate of penetration of ARV regimen into the CNS, and validated as predictor of CSF HIV-1 replication. Results on predictive role of CPE on neurocognitive and clinical outcome were conflicti...

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Detalles Bibliográficos
Autores principales: Libertone, Raffaella, Lorenzini, Patrizia, Balestra, Pietro, Pinnetti, Carmela, Ricottini, Martina, Maddalena Plazzi, Maria, Menichetti, Samanta, Zaccarelli, Mauro, Nicastri, Emanuele, Bellagamba, Rita, Ammassari, Adriana, Antinori, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225401/
https://www.ncbi.nlm.nih.gov/pubmed/25394159
http://dx.doi.org/10.7448/IAS.17.4.19655

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