Analysis of transmitted HIV-1 drug resistance using 454 ultra-deep-sequencing and the DeepChek(®)-HIV system

INTRODUCTION: Next-generation sequencing (NGS) is capable of detecting resistance-associated mutations (RAMs) present at frequencies of 1% or below. Several studies have found that baseline low-frequency RAMs are associated with failure to first-line HAART. One major limitation to the expansion of t...

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Detalles Bibliográficos
Autores principales: Garcia-Diaz, Ana, McCormick, Adele, Booth, Clare, Gonzalez, Dimitri, Sayada, Chalom, Haque, Tanzina, Johnson, Margaret, Webster, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Poster Sessions – Abstract P220
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225408/
https://www.ncbi.nlm.nih.gov/pubmed/25397497
http://dx.doi.org/10.7448/IAS.17.4.19752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225408/
https://www.ncbi.nlm.nih.gov/pubmed/25397497
http://dx.doi.org/10.7448/IAS.17.4.19752

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