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Impact of COX2 genotype, ER status and body constitution on risk of early events in different treatment groups of breast cancer patients

The COX2 rs5277 (306G>C) polymorphism has been associated with inflammation-associated cancers. In breast cancer, tumor COX-2 expression has been associated with increased estrogen levels in estrogen receptor (ER)-positive and activated Akt-pathway in ER-negative tumors. Our study investigated th...

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Detalles Bibliográficos
Autores principales: Markkula, Andrea, Simonsson, Maria, Rosendahl, Ann H, Gaber, Alexander, Ingvar, Christian, Rose, Carsten, Jernström, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225481/
https://www.ncbi.nlm.nih.gov/pubmed/24599585
http://dx.doi.org/10.1002/ijc.28831