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Molecules and mechanisms controlling the active DNA demethylation of the mammalian zygotic genome

The active DNA demethylation in early embryos is essential for subsequent development. Although the zygotic genome is globally demethylated, the DNA methylation of imprinted regions, part of repeat sequences and some gamete-specific regions are maintained. Recent evidence has shown that multiple pro...

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Detalles Bibliográficos
Autores principales: Ma, Jun-Yu, Zhang, Teng, Shen, Wei, Schatten, Heide, Sun, Qing Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225482/
https://www.ncbi.nlm.nih.gov/pubmed/25152302
http://dx.doi.org/10.1007/s13238-014-0095-3