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Molecules and mechanisms controlling the active DNA demethylation of the mammalian zygotic genome
The active DNA demethylation in early embryos is essential for subsequent development. Although the zygotic genome is globally demethylated, the DNA methylation of imprinted regions, part of repeat sequences and some gamete-specific regions are maintained. Recent evidence has shown that multiple pro...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Higher Education Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225482/ https://www.ncbi.nlm.nih.gov/pubmed/25152302 http://dx.doi.org/10.1007/s13238-014-0095-3 |